A novel instrumented multipeg running wheel system, Step-Wheel, for monitoring and controlling complex sequential stepping in mice
نویسندگان
چکیده
منابع مشابه
A novel instrumented multipeg running wheel system, Step-Wheel, for monitoring and controlling complex sequential stepping in mice.
Motor control is critical in daily life as well as in artistic and athletic performance and thus is the subject of intense interest in neuroscience. Mouse models of movement disorders have proven valuable for many aspects of investigation, but adequate methods for analyzing complex motor control in mouse models have not been fully established. Here, we report the development of a novel running-...
متن کاملMonitoring and Controlling Complex Sequential Stepping in Mice
1 A Novel Instrumented Multi-Peg Running Wheel System, Step-Wheel, for 2 Monitoring and Controlling Complex Sequential Stepping in Mice 3 4 Authors: 5 Takashi Kitsukawa, Masatoshi Nagata, Dai Yanagihara, Ryohei Tomioka, 6 Hideko Utsumi, Yasuo Kubota, Takeshi Yagi, Ann M. Graybiel, Tetsuo 7 Yamamori 8 9 Affiliation: 10 Graduate School of Frontier Biosciences, Osaka University, Suita, Japan 11 Gr...
متن کاملArtificial selection for increased wheel-running behavior in house mice.
Replicated within-family selection for increased voluntary wheel running in outbred house mice (Mus domesticus; Hsd:ICR strain) was applied with four high-selected and four control lines (10 families/line). Mice were housed individually with access to activity wheels for a period of 6 days, and selection was based on the mean number of revolutions run on days 5 and 6. Prior to selection, herita...
متن کاملFosB Regulates Wheel Running
FosB is a transcription factor that accumulates in a regionspecific manner in the brain after chronic perturbations. For example, repeated administration of drugs of abuse increases levels of FosB in the striatum. In the present study, we analyzed the effect of spontaneous wheel running, as a model for a natural rewarding behavior, on levels of FosB in striatal regions. Moreover, mice that indu...
متن کاملPlasma adiponectin is increased in mice selectively bred for high wheel-running activity, but not by wheel running per sé.
Mice selectively bred for high wheel-running activity (S) have decreased fat content compared to mice from randomly bred control (C) lines. We explored whether this difference was associated with alterations in levels of circulating hormones involved in regulation of food intake and energy balance, and whether alterations were caused by the presence of a running wheel. Plasma levels of leptin, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2011
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00139.2011